http://physiome.org/model/ 2010-07-30T04:45:44-07:00 http://physiome.org/model/ http://physiome.org/model/lib/images/favicon.ico text/html 2010-07-15T13:39:53-07:00 Bart jardine http://physiome.org/model/doku.php?id=Endocrine_System:Hormones_of_pancreatic_islets:Insulin:Metabolic_Insulin_Signaling_Pathways:model_index&rev=1279226393&do=diff A mathematical model of metabolic insulin signaling pathways based on the work of Ahmad Sedaghat, Arthur Sherman and Michael Quon [2002, AM J Physiol Endocrinol Metab, 283,E1084-E1101]. The model was developed by Maris Lemba [2003] as a project for BIOEN 598, University of Washington. [Illustrative Diagram] text/html 2010-07-08T15:20:14-07:00 Maxwell Neal http://physiome.org/model/doku.php?id=Integrative_Physiology:Highly-integrated_human_with_interventions:model_detail&rev=1278627614&do=diff Go to the model index page This is a closed loop cardiopulmonary system composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a coronary circulation, a pulmonary circulation, airways mechanics, baroreceptors, gas exchange, blood gas handling, peripheral chemoreceptors and selectable interventions (Valsalva maneuver, pericardial removal, penetrating wounds to heart, septal defect, etc.). text/html 2010-05-18T14:56:05-07:00 Bart jardine http://physiome.org/model/doku.php?id=Tutorials:Lung&rev=1274219765&do=diff Mechanics OneAlvLung One Alveolus Lung Lung_RC Lung modeled analogously as electrical RC circuit Lung_RC_Air Lung with Concentration and non-linear compliance 2CompLung_Air Two compartment lung with concentrations and nonlinear compliances Lutchen This model is based on Lutchen et al. A nonlinear model combining pulmonary mechanics and gas concentration dynamics. IEEE Trans. Biomed. Eng. 29: 629-641, 1982.BronchiBronchiolAlvThis model represents airway with a bronchi,a bronchioles, and a alv… text/html 2010-01-21T15:47:40-07:00 Bart jardine http://physiome.org/model/doku.php?id=Transport_Physiology:Whole_organ_models:Goresky:Red_cell_carriage:model_index&rev=1264117660&do=diff Back to Introduction The erythrocyte membrane potentially limits the exchange of solutes between erythrocytes (red blodd cells) and plasma water. The multiple indicator dilution technique can be used to investigate the effect of this barrier on the exchange of tracer substances.